Expresión de búsqueda: GLUCAGON-LIKE PEPTIDE 1 
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Descriptor Inglés:   Glucagon-Like Peptide 1 
Descriptor Español:   Péptido 1 Similar al Glucagón 
Descriptor Portugués:   Peptídeo 1 Semelhante ao Glucagon 
Categoría:   D06.472.317.469.500.500
Definición Inglés:   A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake. 
Acción Farmacológica:   Incretins
 
Nota Histórica Inglés:   2006 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Número del Registro:   50567 
Identificador Único:   D052216 

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